Wednesday 17th, August 2022
canara news

Triple therapy to help fight deadly lung cancer

Published On : 02 Jan 2016


Washington, (IANS) In experimental models of lung cancer, researchers have found that a combination of two drugs plus radiation can help treat resistant lung cancers which are susceptible to therapy.

Although the most common type of lung cancer - non-small cell lung cancer (NSCLC) - has recently seen major treatment advances, other subtypes continue to evade effective treatment.

Now, a new study in mice has shown that cancers with mutations in the gene known as KRAS may benefit from a triple therapy with two experimental drugs plus radiation therapy.

“Currently there is a clinical trial underway to evaluate the combination of two cancer drugs made by two pharma companies for patients with solid tumors and melanoma,” claimed Bo Lu, professor of radiation oncology at Thomas Jefferson University.

“Our study suggests that we may be able to identify non-small cell lung cancer patients who are likely to benefit most from this combination of therapies,” he added.

Roughly 85 percent of all lung cancers belong to the NSCLC type.

Although there have been some advances in treating this disease, only two percent of survivors live five years beyond treatment.

The researchers combined the KRAS-targeting drug with another drug.

Together, Dr Lu's group showed that the combination of the two drugs make these resistant cancer cells susceptible to radiation treatment.

“If you hit one target another can take over. If you hit two, it becomes a lethal bullet," Dr Lu added.

Dr Lu hopes that this research will help identify the patients who could potentially benefit from a triple-therapy treatment.

The results were published in the journal Clinical Cancer Research.

 







More News

Mother-daughter conflict ups suicide risk in abused teen girls: Study
Mother-daughter conflict ups suicide risk in abused teen girls: Study
Novel wearable ultrasound patch monitors BP inside body
Novel wearable ultrasound patch monitors BP inside body
Mental health may not ruin teenagers' friendships: Study
Mental health may not ruin teenagers' friendships: Study

Write your Comments

Disclaimer: Please write your correct name and email address. Kindly do not post any personal, abusive, defamatory, infringing, obscene, indecent, discriminatory or unlawful or similar comments. canaranews.com will not be responsible for any defamatory message posted under this article.

Please note that under 66A of the IT Act, sending offensive or menacing messages through electronic communication service and sending false messages to cheat, mislead or deceive people or to cause annoyance to them is punishable. It is obligatory on CANARANEWS to provide the IP address and other details of senders of such comments, to the authority concerned upon request.

Hence, sending offensive comments using canaranews will be purely at your own risk, and in no way will canaranews.com be held responsible.